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Phenotypes Associated with This Genotype
Genotype
MGI:4453798
Allelic
Composition		 Cd55tm1Song/Cd55tm1Song
Genetic
Background		 involves: 129S6/SvEvTac
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd55tm1Song mutation (2 available); any Cd55 mutation (37 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal complement pathway ( J:76578 )
• erythrocytes show increased susceptibility to antibody-induced lysis by rat, and to a lesser extent, human complement compared to wild-type
• antibody-sensitized erythrocytes exhibit increased C3 deposition compared to wild-type cells

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory