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Phenotypes Associated with This Genotype
Genotype
MGI:4452492
Allelic
Composition
Tg(Thy1-APPSw,Thy1-PSEN1*L166P)21Jckr/0
Tg(Thy1-MAPT*P301S)2541Godt/0
Genetic
Background
B6.Cg-Tg(Thy1-APPSw,Thy1-PSEN1*L166P)21Jckr Tg(Thy1-MAPT*P301S)2541Godt
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(Thy1-APPSw,Thy1-PSEN1*L166P)21Jckr mutation (1 available)
Tg(Thy1-MAPT*P301S)2541Godt mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
nervous system
• at 12 months, mice exhibit a 3- to 4-fold increase in Tau lesions compared with Tg(Thy1-MAPT*P301S)2541Godt mice


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory