Analysis Tools
mortality/aging
|
• fewer than expected mice are present from E14.5 to birth
|
|
• more than half of mice die perinatally
|
renal/urinary system
|
• as early as E15.5, mice develop cysts with squamous cell lining unlike wild-type mice
• cysts develop from glomeruli, proximal tubules, and the thick ascending limb of the loop of Henle and collecting ducts
|
|
• bilaterally in surviving mice
|
|
• mice exhibit a reduction in the nephrogenic zone compared with wild-type mice
|
liver/biliary system
biliary cyst
(
J:158678
)
endocrine/exocrine glands
biliary cyst
(
J:158678
)
growth/size/body
biliary cyst
(
J:158678
)
|
• as early as E15.5, mice develop cysts with squamous cell lining unlike wild-type mice
• cysts develop from glomeruli, proximal tubules, and the thick ascending limb of the loop of Henle and collecting ducts
|
|
• bilaterally in surviving mice
|
