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Phenotypes Associated with This Genotype
Genotype
MGI:4441310
Allelic
Composition		 Stat1tm1Rds/Stat1tm1Rds
Stat2tm1Shnd/Stat2tm1Shnd
Genetic
Background		 involves: 129/Sv * 129S1/Sv * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stat1tm1Rds mutation (4 available); any Stat1 mutation (73 available)
Stat2tm1Shnd mutation (3 available); any Stat2 mutation (41 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased susceptibility to Riboviria infection ( J:66564 )
• mutants succumb to vesicular stomatitis virus (VSV) infection quicker than wild-type or single homozygous mutants

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory