Phenotypes for Lmx1b Sox9 MGI:4441202 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Lmx1b^tm1Rjo/Lmx1b^tm1Zfc Sox9^tm3(cre)Crm/Sox9⁺
Genetic Background	involves: 129S7/SvEvBrd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lmx1b^tm1Rjo mutation (0 available); any Lmx1b mutation (16 available)
Lmx1b^tm1Zfc mutation (0 available); any Lmx1b mutation (16 available)
Sox9^tm3(cre)Crm mutation (1 available); any Sox9 mutation (33 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

skeleton phenotype ( J:158676 )

N	• mice exhibit normal dorsal tendons of the metacarpophalangeal joint

abnormal metacarpal bone morphology ( J:158676 )

• mice exhibit partial duplication of sesamoid bones at the metacarpophalangeal joint compared with wild-type mice

• mice exhibit abnormal tips of the metacarpals

limbs/digits/tail

abnormal metacarpal bone morphology ( J:158676 )

• mice exhibit partial duplication of sesamoid bones at the metacarpophalangeal joint compared with wild-type mice

• mice exhibit abnormal tips of the metacarpals

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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