Phenotypes Associated with This Genotype

Genotype
MGI:4440958

• Allelic Composition: Runx1^tm1.1Stkd/Runx1^tm1.1Stkd; Tg(Prrx1-cre)1Cjt/0
• Genetic Background: involves: C57BL/6J * SJL/J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

abnormal sternum morphology ( J:158761 )

• at 2 weeks of age, sternal development is delayed compared to in wild-type mice

• however, sternal development is normal by 3 weeks of age

abnormal xiphoid process morphology ( J:158761 )

• not mineralized in newborn mice

abnormal skeleton development ( J:158761 )

• at E14.5, sternal bar development is delayed compared to in wild-type mice

abnormal bone mineralization ( J:158761 )

• the xiphoid process is not mineralized in newborn mice unlike in wild-type mice

• however, by 3 weeks of age mice exhibit normal skeletal morphology