About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:4440933
Allelic
Composition		 Bhlhe22tm2.1Meg/Bhlhe22tm2.1Meg
Tg(Pax2-cre)1Akg/0
Genetic
Background		 involves: 129
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bhlhe22tm2.1Meg mutation (0 available); any Bhlhe22 mutation (12 available)
Tg(Pax2-cre)1Akg mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
behavior/neurological
excessive scratching ( J:158273 )
• resulting in skin lesions in most animals
abnormal chemical nociception ( J:158273 )
• mice show excessive scratching in response to pruritic agents

integument
skin lesions ( J:158273 )
• animals display self-inflicted skin lesions

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory