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Phenotypes Associated with This Genotype
Genotype
MGI:4438779
Allelic
Composition		 Cd84tm1Pls/Cd84tm1Pls
Tg(TcraTcrb)425Cbn/?
Genetic
Background		 B6.Cg-Cd84tm1Pls Tg(TcraTcrb)425Cbn
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Cd84tm1Pls mutation (0 available); any Cd84 mutation (56 available)
Tg(TcraTcrb)425Cbn mutation (7 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
abnormal CD4-positive, alpha-beta T cell physiology ( J:157915 )
• when B cells are used as the antigen presenting cells, T cells are significantly less efficient in forming conjugates as compared to their wild-type counterparts

hematopoietic system
abnormal CD4-positive, alpha-beta T cell physiology ( J:157915 )
• when B cells are used as the antigen presenting cells, T cells are significantly less efficient in forming conjugates as compared to their wild-type counterparts

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/13/2026
MGI 6.24 		The Jackson Laboratory