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Phenotypes Associated with This Genotype
Genotype
MGI:4437425
Allelic
Composition		 Nodaltm1Rob/Nodal+
Tgif1tm1Dwot/Tgif1tm1Dwot
Tgif2tm1Dwot/Tgif2tm1Dwot
Genetic
Background		 involves: 129S/SvEv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nodaltm1Rob mutation (2 available); any Nodal mutation (41 available)
Tgif1tm1Dwot mutation (0 available); any Tgif1 mutation (49 available)
Tgif2tm1Dwot mutation (0 available); any Tgif2 mutation (40 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
embryo
embryo phenotype ( J:157256 )
N
• unlike in double null mice wild-type for Nodal, the embryonic cavity has formed by E8.5 and a distinct AP axis is present

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
01/20/2026
MGI 6.24 		The Jackson Laboratory