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Phenotypes Associated with This Genotype
Genotype
MGI:4436743
Allelic
Composition		 Npc1tm1.2Apl/Npc1tm1.2Apl
Genetic
Background		 C57BL/6-Npc1tm1.2Apl
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Npc1tm1.2Apl mutation (0 available); any Npc1 mutation (72 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
premature death ( J:157113 )
• similar to in Npc1m1N homozygotes

behavior/neurological

growth/size/body
weight loss ( J:157113 )
• similar to in Npc1m1N homozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory