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Phenotypes Associated with This Genotype
Genotype
MGI:4431220
Allelic
Composition
PhexHyp/Phex+
Tg(Bglap2-Phex)1Ldq/?
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
PhexHyp mutation (2 available); any Phex mutation (21 available)
Tg(Bglap2-Phex)1Ldq mutation (0 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• despite increased Phex expression in osteoblasts these mice still have the diminished serum phosphate of hypophosphatemia mutants

skeleton
• despite increased Phex expression in osteoblasts these mice have the same skeletal defects of hypophosphatemia mice including reduced bone mineral density, smaller than normal caudal vertebrae, increased widening and irregularity of growth plates, rickets and osteomalacia


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory