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Phenotypes Associated with This Genotype
Genotype
MGI:4430834
Allelic
Composition		 Bmp2tm1Brd/Bmp2tm1.1Mis
Gfi1tm1(cre)Gan/Gfi1+
Genetic
Background		 involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bmp2tm1.1Mis mutation (0 available); any Bmp2 mutation (25 available)
Bmp2tm1Brd mutation (0 available); any Bmp2 mutation (25 available)
Gfi1tm1(cre)Gan mutation (0 available); any Gfi1 mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
increased or absent threshold for auditory brainstem response ( J:156945 )
• a 6.5 dB shift in threshold is detected at 16kHz in 3-6 month-old mice compared to controls; at 9-10 months, hearing thresholds are comparable to controls

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/13/2026
MGI 6.24 		The Jackson Laboratory