Phenotypes Associated with This Genotype

Genotype
MGI:4430400

• Allelic Composition: Bnip3l^tm1.1Gwd/Bnip3l^tm1.1Gwd; Tg(Myh6-Gnaq)#Gwd/0
• Genetic Background: involves: 129 * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

premature death ( J:145086 )

• mice exhibit premature death with wild-type mice that is not as severe as in Tg(Myh6-Gnaq)Gwd mice

cardiovascular system

cardiovascular system phenotype ( J:145086 )

N • mice do not exhibit ventricular remodeling unlike Tg(Myh6-Gnaq)Gwd mice

enlarged heart ( J:145086 )

• not as severe as in Tg(Myh6-Gnaq)Gwd mice

dilated heart ( J:145086 )

• not as severe as in Tg(Myh6-Gnaq)Gwd mice

decreased cardiac muscle contractility ( J:145086 )

• not as severe as in Tg(Myh6-Gnaq)Gwd mice

muscle

decreased cardiac muscle contractility ( J:145086 )

• not as severe as in Tg(Myh6-Gnaq)Gwd mice

increased cardiomyocyte apoptosis ( J:145086 )

• not as severe as in Tg(Myh6-Gnaq)Gwd mice

cellular

increased cardiomyocyte apoptosis ( J:145086 )

• not as severe as in Tg(Myh6-Gnaq)Gwd mice

growth/size/body

enlarged heart ( J:145086 )

• not as severe as in Tg(Myh6-Gnaq)Gwd mice