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Phenotypes Associated with This Genotype
Genotype
MGI:4430237
Allelic
Composition		 Foxp3tm7.2Ayr/Foxp3+
Genetic
Background		 involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxp3tm7.2Ayr mutation (0 available); any Foxp3 mutation (55 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hematopoietic system
decreased regulatory T cell number ( J:156942 )
• marked decrease in T reg cells expressing the mutant allele in females

immune system
decreased regulatory T cell number ( J:156942 )
• marked decrease in T reg cells expressing the mutant allele in females

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory