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Phenotypes Associated with This Genotype
Genotype
MGI:4429891
Allelic
Composition		 Espnje/Espnje
Genetic
Background		 involves: 129X1/SvJ * JE/LeJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Espnje mutation (2 available); any Espn mutation (34 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
increased or absent threshold for auditory brainstem response ( J:78812 )
• ABR assessment on F2 homozygotes at 5 to 6 weeks of age shows no signs of hearing indicating an absence of ameliorating modifiers
abnormal vestibular system physiology ( J:78812 )
• a normal ratio of F2 offspring display the abnormal vestibular phenotype indicating the absence of ameliorating modifiers

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory