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Phenotypes Associated with This Genotype
Genotype
MGI:4421818
Allelic
Composition		 Klf5tm2.1Rng/Klf5tm2.1Rng
Tg(Myh6-cre)2182Mds/0
Genetic
Background		 involves: C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Klf5tm2.1Rng mutation (0 available); any Klf5 mutation (38 available)
Tg(Myh6-cre)2182Mds mutation (3 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Cardiomyocyte-specific deletion of Klf5 does not alter pressure overload-induced hypertrophy in Klf5tm2.1Rng/Klf5tm2.1Rng Tg(Myh6-cre)2182Mds/0 mice

cardiovascular system
cardiovascular system phenotype ( J:156696 )
N
• mice exhibit a normal response to low-intensity transverse aortic constriction

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory