Phenotypes Associated with This Genotype

Genotype
MGI:4421774

• Allelic Composition: Lmo2^tm2(cre)Thr/Lmo2⁺
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

abnormal common myeloid progenitor cell morphology ( J:155870 )

• decreased granulocyte/macrophage colony-forming units

abnormal megakaryocyte progenitor cell morphology ( J:155870 )

• megakaryocyte colony-forming units numbers of are depressed in the bone marrow

decreased erythrocyte cell number ( J:155870 )

• a reduction in the number of circulating RBCs

decreased hemoglobin content ( J:155870 )

increased mean corpuscular volume ( J:155870 )

decreased granulocyte number ( J:155870 )

• total granulocyte numbers are lower in the blood

thrombocytopenia ( J:155870 )

decreased monocyte cell number ( J:155870 )

• total monocyte numbers are lower in the blood

immune system

decreased granulocyte number ( J:155870 )

• total granulocyte numbers are lower in the blood

decreased monocyte cell number ( J:155870 )

• total monocyte numbers are lower in the blood