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Phenotypes Associated with This Genotype
Genotype
MGI:4421577
Allelic
Composition
Grin1tm2Stl/Grin1tm2Stl
Tg(Ppp1r2-cre)4127Nkza/0
Genetic
Background
involves: 129S4/SvJae * C57BL/6N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Grin1tm2Stl mutation (1 available); any Grin1 mutation (64 available)
Tg(Ppp1r2-cre)4127Nkza mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
N
• adult mice (25-29 weeks of age) do not show behavioral deficits and display normal social recognition
• mice at more than 32 weeks of age do not deficits in nest building behavior
• mice do not show anxiety-like behaviors

nervous system
N
• mice display normal prepulse inhibition of the auditory startle reflex
• no differences in mean firing rates or cross-correlation values of pyramidal neurons are detected relative to controls


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory