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Phenotypes Associated with This Genotype
Genotype
MGI:4421423
Allelic
Composition		 Lmo4tm1Gan/Lmo4tm2.1Gan
Foxg1tm1(cre)Skm/Foxg1+
Genetic
Background		 involves: 129P2/OlaHsd * 129S4/SvJaeSor * 129S6/SvEvTac * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Foxg1tm1(cre)Skm mutation (2 available); any Foxg1 mutation (30 available)
Lmo4tm1Gan mutation (0 available); any Lmo4 mutation (6 available)
Lmo4tm2.1Gan mutation (0 available); any Lmo4 mutation (6 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
hearing/vestibular/ear
abnormal inner ear morphology ( J:156733 )
• at E15.5, mice exhibit vestibular defects observed in Lmo4tm1Gan homozygotes
abnormal semicircular canal ampulla morphology ( J:156733 )
• at E15.5, mice lack anterior and posterior ampullae unlike in wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory