Phenotypes for Brca1 Cdkn1a MGI:4420437 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Brca1^tm1Mak/Brca1^tm1Mak Cdkn1a^tm1Tyj/Cdkn1a^tm1Tyj
Genetic Background	involves: 129P2/OlaHsd * 129S2/SvPas

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Brca1^tm1Mak mutation (0 available); any Brca1 mutation (113 available)
Cdkn1a^tm1Tyj mutation (3 available); any Cdkn1a mutation (63 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

embryonic lethality during organogenesis, complete penetrance ( J:41254 )

• mice die between E9.5 and E11.5

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 01/06/2026 MGI 6.24