Phenotypes Associated with This Genotype

Genotype
MGI:4420259

• Allelic Composition: Tg(Thy1-APPSwe)1Lngn/0
• Genetic Background: involves: C57BL/6 * CBA

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

amyloid beta deposits ( J:105265 )

• few intraneuronal amyloid beta aggregates in layers of the cerebral cortex in 2-month old animals while at 15 months only occasional cortical neurons show immunoreactivity

• at 15-17 months, no or very few diffuse amyloid beta deposits are detected

homeostasis/metabolism

amyloid beta deposits ( J:105265 )

• few intraneuronal amyloid beta aggregates in layers of the cerebral cortex in 2-month old animals while at 15 months only occasional cortical neurons show immunoreactivity

• at 15-17 months, no or very few diffuse amyloid beta deposits are detected