Phenotypes for Esr1 Esr2 Inha MGI:4418903 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Esr1^tm1Ksk/Esr1^tm1Ksk Esr2^tm1Unc/Esr2^tm1Unc Inha^tm1Bay/Inha⁺
Genetic Background	involves: 129P2/OlaHsd * 129S6/SvEvTac * 129S7/SvEvBrd

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Esr1^tm1Ksk mutation (2 available); any Esr1 mutation (69 available)
Esr2^tm1Unc mutation (4 available); any Esr2 mutation (35 available)
Inha^tm1Bay mutation (0 available); any Inha mutation (11 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

reproductive system

abnormal ovary morphology ( J:84989 )

• ovaries develop tubule-like structures unlike in wild-type mice

increased ovary tumor incidence ( J:84989 )

• in one mouse

neoplasm

increased ovary tumor incidence ( J:84989 )

• in one mouse

endocrine/exocrine glands

abnormal ovary morphology ( J:84989 )

• ovaries develop tubule-like structures unlike in wild-type mice

increased ovary tumor incidence ( J:84989 )

• in one mouse

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 01/13/2026 MGI 6.24