Phenotypes Associated with This Genotype

Genotype
MGI:4418702

• Allelic Composition: Tardbp^tm1.1Ckjs/Tardbp^tm1.1Ckjs
• Genetic Background: involves: C57BL/6J * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

Tardbp^tm1.1Ckjs/Tardbp^tm1.1Ckjs embryos show defective development of the inner cell mass in vitro

mortality/aging

embryonic lethality, complete penetrance ( J:155958 )

• embryonic lethal between E3.5 and E6.5

embryo

absent inner cell mass proliferation ( J:155958 )

• E3.5 embryos cultured for 3 days on adhered trophoblast giant cells fail to form the proliferative ICM

cellular

absent inner cell mass proliferation ( J:155958 )

• E3.5 embryos cultured for 3 days on adhered trophoblast giant cells fail to form the proliferative ICM