Phenotypes Associated with This Genotype

Genotype
MGI:4418247

• Allelic Composition: Lfng^tm1.2Egan/Lfng^tm1.2Egan
• Genetic Background: involves: 129 * 129S4/SvJaeSor * FVB/N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

prenatal lethality, incomplete penetrance ( J:155893 )

• fewer than expected mice are born

respiratory system

abnormal lung development ( J:155893 )

• Background Sensitivity: abnormal lung development is more severe on an FVB background

impaired lung alveolus development ( J:155893 )

• mice exhibit similar alveolar development defects as in Lfng^tm1Grid homozygotes

embryo

abnormal somite development ( J:155893 )

• mice exhibit similar somite patterning defect as in Lfng^tm1Grid homozygotes