About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:4418247
Allelic
Composition		 Lfngtm1.2Egan/Lfngtm1.2Egan
Genetic
Background		 involves: 129 * 129S4/SvJaeSor * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Lfngtm1.2Egan mutation (0 available); any Lfng mutation (32 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
prenatal lethality, incomplete penetrance ( J:155893 )
• fewer than expected mice are born

respiratory system
abnormal lung development ( J:155893 )
• Background Sensitivity: abnormal lung development is more severe on an FVB background
impaired lung alveolus development ( J:155893 )
• mice exhibit similar alveolar development defects as in Lfngtm1Grid homozygotes

embryo
abnormal somite development ( J:155893 )
• mice exhibit similar somite patterning defect as in Lfngtm1Grid homozygotes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory