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Phenotypes Associated with This Genotype
Genotype
MGI:4417856
Allelic
Composition
Slc6a4tm1(cre)Xz/Slc6a4tm1(cre)Xz
Genetic
Background
involves: 129S1/Sv * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Slc6a4tm1(cre)Xz mutation (2 available); any Slc6a4 mutation (26 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• 75% of mice die with the first week after birth

cardiovascular system
• at E18.5, mice exhibit an increase in collagen accumulation in the myocardium and valvular and perivascular regions of the heart unlike wild-type mice

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
sudden infant death syndrome DOID:9007 OMIM:272120
J:155633


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/08/2017
MGI 6.10
The Jackson Laboratory