About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:4415622
Allelic
Composition		 Etv4tm1Arbr/Etv4tm1Arbr
Etv5tm1Hass/Etv5+
Tg(Hoxb7-Venus*)17Cos/0
Genetic
Background		 involves: 129S1/Sv * C57BL/6J * CBA/J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Etv4tm1Arbr mutation (0 available); any Etv4 mutation (40 available)
Etv5tm1Hass mutation (0 available); any Etv5 mutation (271 available)
Tg(Hoxb7-Venus*)17Cos mutation (1 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
renal/urinary system
absent kidney ( J:155594 )
• in most mice
abnormal ureter development ( J:155594 )
• at E11.5 to E12.5, 16% of ureteric buds are absent, 40% show no branching, 19% exhibit retarded branching compared to in wild-type mice
• when kidneys form they contain reduced numbers and irregularly patterned ureteric bud tips unlike in wild-type mice
• cultured ureteric buds fail to develop unlike wild-type samples and samples containing only one to two mutant alleles

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
05/28/2024
MGI 6.13 		The Jackson Laboratory