Phenotypes for Gli2 Gli3 MGI:4414946 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Gli2^tm1Alj/Gli2^tm1Alj Gli3^Xt/Gli3⁺
Genetic Background	involves: 101/H * 129S1/Sv * 129X1/SvJ * C3H/HeH * C57BL * CBA/H * Swiss Webster

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gli2^tm1Alj mutation (0 available); any Gli2 mutation (169 available)
Gli3^Xt mutation (1 available); any Gli3 mutation (80 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

nervous system

increased neuronal precursor cell number ( J:87948 )

• the motor neuron progenitor domain is greatly expanded dorsally however motor neurons appear to differentiate normally

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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