Phenotypes Associated with This Genotype

Genotype
MGI:4414942

• Allelic Composition: Gli1^tm2Alj/Gli1^tm2Alj; Gli2^{tm5.1(GLI3)Alj}/Gli2^{tm5.1(GLI3)Alj}
• Genetic Background: involves: 129S6/SvEvTac * Swiss Webster

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

absent floor plate ( J:87948 )

• absence of floor plate cells throughout the anterior/posterior (A/P) axis of the spinal cord

abnormal ventral interneuron 3 morphology ( J:87948 )

• only a very small number of V3 interneurons are seen in the ventral midline of the spinal cord

embryo

absent floor plate ( J:87948 )

• absence of floor plate cells throughout the anterior/posterior (A/P) axis of the spinal cord