Phenotypes Associated with This Genotype

Genotype
MGI:4414941

• Allelic Composition: Gli2^tm5(GLI3)Alj/Gli2^tm1Alj
• Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Swiss Webster

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

embryo

abnormal neural tube morphology ( J:87948 )

• phenotype is similar to that of Gli2^tm1Alj mutant embryos, indicating that a low level of Gli3 is not enough to substitute for Gli2

absent floor plate ( J:87948 )

• absence of floor plate cells throughout the anterior/posterior (A/P) axis of the spinal cord

nervous system

abnormal neural tube morphology ( J:87948 )

• phenotype is similar to that of Gli2^tm1Alj mutant embryos, indicating that a low level of Gli3 is not enough to substitute for Gli2

absent floor plate ( J:87948 )

• absence of floor plate cells throughout the anterior/posterior (A/P) axis of the spinal cord