Phenotypes for Dbh Th MGI:4414756 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Dbh^tm2(Th)Rpa/Dbh⁺ Th^tm5Rpa/Th^tm5Rpa
Genetic Background	involves: 129S4/SvJaeSor

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dbh^tm2(Th)Rpa mutation (1 available); any Dbh mutation (15 available)
Th^tm5Rpa mutation (0 available); any Th mutation (58 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

abnormal avoidance learning behavior ( J:154773 )

• conditioned place aversion to the KOR agonist U50,488 is slightly but significantly increased compared to littermate controls

homeostasis/metabolism

decreased dopamine level ( J:154773 )

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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