Phenotypes Associated with This Genotype

Genotype
MGI:4414673

• Allelic Composition: Gt(ROSA)26Sor^{tm2(Gli2*)Flng}/Gt(ROSA)26Sor⁺; Tg(Col2a1-cre)3Amc/0
• Genetic Background: involves: 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

decreased length of long bones ( J:154905 )

• 10% to 15% at E18.5

abnormal cartilage development ( J:154905 )

• as determined by marker expression, cartilage growth in long bones is reduced due to premature onset of hypertrophy compared with wild-type mice

abnormal long bone epiphyseal plate proliferative zone ( J:154905 )

• decreased at E14.5 and E18.5

decreased width of hypertrophic chondrocyte zone ( J:154905 )

• at E18.5

increased width of hypertrophic chondrocyte zone ( J:154905 )

• at E14.5

growth/size/body

decreased body size ( J:154905 )