Phenotypes Associated with This Genotype

Genotype
MGI:4413456

• Allelic Composition: Bax^tm1Sjk/Bax^tm1Sjk; Ngf^tm1Gne/Ngf^tm1Gne
• Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal neuron morphology ( J:154926 )

• at E14.5, extension of hind limb nerves is defective compared to in wild-type mice

• extension of the third digital branch of the deep peroneal nerve is reduced 27% compared to in wild-type mice

• extension of the lateral plantar nerve is reduced 13% compared to in wild-type mice

• at E15.5, the number and order of branches in the medial digital branch of the lateral plantar nerve in the fifth digit are impaired compared to in wild-type mice

abnormal sensory neuron innervation pattern ( J:170402 )

• mice exhibit excessive nociceptor axons in deep spinal cord layers compared with wild-type mice