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Phenotypes Associated with This Genotype
Genotype
MGI:4412011
Allelic
Composition		 Ppargtm1Rev/Ppargtm2Mae
Genetic
Background		 involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ppargtm1Rev mutation (1 available); any Pparg mutation (39 available)
Ppargtm2Mae mutation (0 available); any Pparg mutation (39 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
increased systemic arterial blood pressure ( J:154767 )
• in males and females at 4 months of age
• overall, decreased Pparg expression correlates with increased blood pressure

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/07/2024
MGI 6.23 		The Jackson Laboratory