Phenotypes Associated with This Genotype

Genotype
MGI:4367612

• Allelic Composition: Chat/Slc18a3^tm1.1Vpra/Chat⁺
• Genetic Background: involves: 129S4/SvJae * C57BL/6J

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

increased acetylcholine level ( J:153908 )

• increased intracellular acetylcholine level in the brains of adult mice

nervous system

abnormal miniature endplate potential ( J:171696 )

• miniature endplate potential amplitude and frequency are increased compared to in wild-type mice

behavior/neurological

behavior/neurological phenotype ( J:171696 )

N • mice exhibit normal grip force, wire-hanging, gait, and locomotion