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Phenotypes Associated with This Genotype
Genotype
MGI:4366932
Allelic
Composition		 Nos1tm1Plh/Nos1tm1Plh
Tg(RHO-VEGFA)V-6Camp/0
Genetic
Background		 involves: 129S4/SvJae * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nos1tm1Plh mutation (3 available); any Nos1 mutation (85 available)
Tg(RHO-VEGFA)V-6Camp mutation (0 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal angiogenesis ( J:106207 )
• compared to mice carrying Tg(RHO-VEGFA)V-6Camp and heterozygous for Nos1tm1Plh neovascularization of the retina is significantly reduced

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory