Phenotypes Associated with This Genotype

Genotype
MGI:4366927

• Allelic Composition: Tg(SOD1)76Dpr/0
• Genetic Background: B6.Cg-Tg(SOD1)76Dpr

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

decreased susceptibility to ischemic brain injury ( J:128835 )

• functional deficits following middle cerebral artery obstruction are reduced compared to wild-type controls

decreased cerebral infarct size ( J:128835 )

• infarction sized induced by middle cerebral artery obstruction is reduced compared to wild-type controls

• infarct size is also reduced compared to Nos1 null mice

homeostasis/metabolism

decreased susceptibility to ischemic brain injury ( J:128835 )

• functional deficits following middle cerebral artery obstruction are reduced compared to wild-type controls

decreased cerebral infarct size ( J:128835 )

• infarction sized induced by middle cerebral artery obstruction is reduced compared to wild-type controls

• infarct size is also reduced compared to Nos1 null mice