Phenotypes Associated with This Genotype

Genotype
MGI:4366770

• Allelic Composition: tch/tch
• Genetic Background: involves: A * BALB/c

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

growth/size/body

disproportionate dwarf ( J:11215 )

limbs/digits/tail

short humerus ( J:11215 )

short ulna ( J:11215 )

short femur ( J:11215 )

short fibula ( J:11215 )

short tibia ( J:11215 )

short limbs ( J:11215 )

short tail ( J:11215 )

• tail has normal taper but is short and thick

skeleton

abnormal appendicular skeleton morphology ( J:11215 )

• affected mice can be distingished from normal siblings by 7 days of age

• abnormal skeletal development gives older mice a "dumpy" appearance but does not influence weight

decreased length of long bones ( J:11215 )

short humerus ( J:11215 )

short ulna ( J:11215 )

short femur ( J:11215 )

short fibula ( J:11215 )

short tibia ( J:11215 )

abnormal pectoral girdle bone morphology ( J:11215 )

• some bone elements are shortened

abnormal pelvic girdle bone morphology ( J:11215 )

• width of elements are reduced to 39% and 58% of normal for females and males respectively

• partial or complete failure of ischium and pubic bone to fuse

• bones are significantly thinner compared with normal siblings