Analysis Tools
vision/eye
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• thickened at E14.5
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• lens tissue is reduced, opaque, and shapeless compared to in wild-type mice
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• at E14.5, the lens is slightly more elongated than in wild-type mice
• at E15.5, transitional zone cells are disorganized unlike in wild-type mice
• anterior lens epithelial cells fail to exit the cell cycle at the equator unlike in wild-type mice
• anterior lens epithelial cells fail to differentiate and accumulate at the lens equator and in the posterior lens unlike in wild-type mice
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• anterior lens epithelial cells fail to exit the cell cycle at the equator unlike in wild-type mice
• anterior lens epithelial cells fail to differentiate and accumulate at the lens equator and in the posterior lens unlike in wild-type mice
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• lens fiber formation is arrested from E14.5 unlike in wild-type mice
• at P4, few fiber cells are found in the lenses unlike in wild-type mice
• at P30, no lens fiber cells are detected unlike in wild-type mice
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small lens
(
J:152850
)
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• at E14.5, mice exhibit small lenses compared to in wild-type mice
• lens tissue is decreased compared to in wild-type mice
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• 65% smaller by circumference compared with wild-type eyes
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cellular
