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Phenotypes Associated with This Genotype
Genotype
MGI:4366243
Allelic
Composition		 Ptgs1tm1Unc/Ptgs1tm1Unc
Genetic
Background		 involves: 129/Sv * 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ptgs1tm1Unc mutation (0 available); any Ptgs1 mutation (44 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
homeostasis/metabolism phenotype ( J:124756 )
N
• bone marrow cultures exhibit normal prostaglandin production in response to stimulation with 1,25-dihydroxyvitamin D3 (1,25-D) or parathyroid hormone (PTH)

skeleton
skeleton phenotype ( J:124756 )
N
• bone marrow cultures exhibit normal TRAP+ mononuclear cells (osteoclast) production in response to stimulation with 1,25-dihydroxyvitamin D3 (1,25-D) or parathyroid hormone (PTH)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory