immune system
• 21 days post-infection with M. tuberculosis, mice exhibit lower TNF levels compared with similarly treated wild-type mice
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• 21 days after infection with M. tuberculosis, lung bacterial counts are 5 to 31 times in similarly treated wild-type mice
• 21 days post-infection with M. tuberculosis, mice exhibit lower TNF levels compared with similarly treated wild-type mice
• 42 days after infection with M. tuberculosis, lung bacterial counts are 3 to 12 times in similarly treated wild-type mice
• however, M. tuberculosis infected mice exhibit normal bacterial colonization of the spleen, formation of granulomatous lesions, and mortality
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homeostasis/metabolism
• 21 days post-infection with M. tuberculosis, mice exhibit lower TNF levels compared with similarly treated wild-type mice
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