Phenotypes for Hoxc8 MGI:4365821 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Hoxc8^{tm4(Hoxc9)Jepl}/Hoxc8⁺
Genetic Background	involves: 129S1/Sv * C57BL/6

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxc8^{tm4(Hoxc9)Jepl} mutation (0 available); any Hoxc8 mutation (8 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

skeleton

abnormal sternocostal joint morphology ( J:153560 )

• unlike in wild-type mice, one of the eighth ribs in some mice attach to the sternum

increased rib number ( J:153560 )

• some mice have extra partial ribs extending from C7 unlike wild-type mice

cervical vertebral transformation ( J:153560 )

• mice have extra ribs extending from C7 unlike wild-type mice

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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