Phenotypes Associated with This Genotype

Genotype
MGI:4365787

• Allelic Composition: skp/skp
• Genetic Background: CXB5/ByJ-skp/GrsrJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skp/skp mice (left) are small, walk on their toes and have impaired balance

mortality/aging

postnatal lethality, incomplete penetrance ( J:153578 )

• usually die by 4 weeks of age

behavior/neurological

impaired balance ( J:153578 )

abnormal gait ( J:153578 )

• mutants walk on their toes

reproductive system

abnormal spermiogenesis ( J:153578 )

♂

growth/size/body

decreased body size ( J:153578 )

hematopoietic system

thymus atrophy ( J:153578 )

immune system

thymus atrophy ( J:153578 )

nervous system

abnormal myelin sheath morphology ( J:153578 )

• underdeveloped myelin

endocrine/exocrine glands

thymus atrophy ( J:153578 )