Phenotypes Associated with This Genotype

Genotype
MGI:4362036

• Allelic Composition: Npy2r^tm1.1Hhz/Npy2r^tm1.1Hhz; Npy4r^tm1.1Hhz/Npy4r^tm1.1Hhz
• Genetic Background: involves: 129X1/SvJ * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

increased circulating insulin-like growth factor I level ( J:129609 )

• after fasting compared with similarly treated wild-type mice

increased growth hormone level ( J:129609 )

• pituitary gland cell growth hormone levels are increased in fasting mice compared to non-fasting mice and unlike in similarly treated wild-type mice

• pituitary gland cell growth hormone levels are increased in nonfasting mice compared with wild-type mice

abnormal testosterone level ( J:129609 )

• testosterone levels in Leydig cells are increased in fasting mice compared to in similarly treated wild-type mice