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Phenotypes Associated with This Genotype
Genotype
MGI:4361709
Allelic
Composition		 Ins1tm1Jja/Ins1tm1Jja
Ins2tm1.1Mnt/Ins2tm1.1Mnt
Genetic
Background		 involves: 129S2/SvPas * 129S4/SvJaeSor * C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ins1tm1Jja mutation (5 available); any Ins1 mutation (50 available)
Ins2tm1.1Mnt mutation (0 available); any Ins2 mutation (90 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, complete penetrance ( J:152798 )
• double homozygous mice die 2-3 days after birth

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory