nervous system
• tamoxifen treated mice exhibit increased apoptosis in the granular layer of the cerebellum, cortex of telencephalon, white matter and midbrain unlike similarly treated and untreated control mice
• however, ventricular zone cells and their neurogenesis are normal in tamoxifen treated mice
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growth/size/body
• tamoxifen treated mice exhibit reduced body weight compared with untreated and treated control mice
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behavior/neurological
cellular
• tamoxifen treated mice exhibit increased apoptosis in the granular layer of the cerebellum, cortex of telencephalon, white matter and midbrain unlike similarly treated and untreated control mice
• however, ventricular zone cells and their neurogenesis are normal in tamoxifen treated mice
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