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Phenotypes Associated with This Genotype
Genotype
MGI:4360217
Allelic
Composition		 X/Yaa
Genetic
Background		 (NZB x B6.SB/Le-Yaa)F1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Yaa mutation (23 available); any Yaa mutation (27 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased monocyte cell number ( J:129409 )
• CD11b+ monocyte numbers increase as mice age with a 3-fold increase by 10 months of age

hematopoietic system
increased monocyte cell number ( J:129409 )
• CD11b+ monocyte numbers increase as mice age with a 3-fold increase by 10 months of age

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory