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Phenotypes Associated with This Genotype
Genotype
MGI:4359865
Allelic
Composition		 Mir208atm1.1Dzw/Mir208atm1.1Dzw
Genetic
Background		 involves: C57BL/6 * FVB/N
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mir208atm1.1Dzw mutation (0 available); any Mir208a mutation (2 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
cardiovascular system phenotype ( J:152696 )
N
• no gross cardiac morphological abnormalities are detected although expression of Myh7 is decreased
prolonged PR interval ( J:152696 )
• prolongation of the PR interval is seen indicating a first degree atrioventricular (AV) block
absent P wave ( J:152696 )
• about 80% of mice lack P waves preceding QRS complexes

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory