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Phenotypes Associated with This Genotype
Genotype
MGI:4359616
Allelic
Composition		 Ryr2tm1.1Wex/Ryr2tm1.1Wex
Genetic
Background		 involves: 129S7/SvEvBrd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ryr2tm1.1Wex mutation (0 available); any Ryr2 mutation (325 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cardiovascular system
abnormal response of heart to induced stress ( J:152544 )
• mice are more resistant to pacing-induced atrial fibrillation in the presence of cholinergic stimulation with carbachol compared with similarly treated wild-type mice

homeostasis/metabolism
abnormal response of heart to induced stress ( J:152544 )
• mice are more resistant to pacing-induced atrial fibrillation in the presence of cholinergic stimulation with carbachol compared with similarly treated wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory