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Phenotypes Associated with This Genotype
Genotype
MGI:4359484
Allelic
Composition		 Pdx1tm1Cvw/Pdx1tm1.1Stof
Genetic
Background		 involves: 129/Sv * 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pdx1tm1.1Stof mutation (0 available); any Pdx1 mutation (35 available)
Pdx1tm1Cvw mutation (1 available); any Pdx1 mutation (35 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Pancreatic hypoplasia in Pdx1tm1Cvw/Pdx1tm1.1Stof mice

endocrine/exocrine glands
small pancreas ( J:152582 )
• small compared to in wild-type mice but not as small as in Pdx1tm1Cvw homozygotes
decreased pancreas weight ( J:152582 )
• decreased weight compared to in wild-type mice but not as much as in Pdx1tm1Cvw homozygotes

homeostasis/metabolism
hyperglycemia ( J:152582 )
• at birth

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory