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Phenotypes Associated with This Genotype
Genotype
MGI:4358796
Allelic
Composition		 Pla2g4atm1Jvb/Pla2g4atm1Jvb
Genetic
Background		 involves: 129S4/SvJae * C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Pla2g4atm1Jvb mutation (0 available); any Pla2g4a mutation (63 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
decreased incidence of tumors by chemical induction ( J:91526 )
• after 19 weeks of treatment with urethane, mice develop 43% fewer lung tumors compared with similarly treated wild-type mice

homeostasis/metabolism
decreased incidence of tumors by chemical induction ( J:91526 )
• after 19 weeks of treatment with urethane, mice develop 43% fewer lung tumors compared with similarly treated wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
07/29/2025
MGI 6.24 		The Jackson Laboratory